Answer to a Homeopath's Criticism

Recently I was treated to a rambling, disjointed letter from Mme Ginette Beaulieu, President of the “Syndicat professionnel des homeopathes du Quebec” in response to my series of columns on homeopathy in the Montreal Gazette.  I will ascribe the undignified and slanderous nature of the letter to the writer’s lack of familiarity with academic and professional demeanor and will overlook the crude attempt at personal defamation. 

It is hard to know just how to respond to Mme Beaulieu’s rant, since she presents so many inviting targets.  She parrots the usual arguments raised by the defenders of homeopathy, apparently unaware that each one has been extensively addressed and deflated by experts around the world.  In his article in The Lancet (1), and in a more elaborate version in the Guardian (2), Dr. Ben Goldacre deftly skewers homeopathic claims and highlights the usual pattern of alternative practitioners’ juvenile reaction to criticism:

“With alternative therapists, when you point out a problem with the evidence, people don't engage with you about it, or read and reference your work. They get into a huff. They refuse to answer calls or email queries. They wave their hands and mutter sciencey words such as "quantum" and "nano". They accuse you of being a paid plant from some big pharma conspiracy. They threaten to sue you. They shout, "What about thalidomide, science boy?", they cry, they call you names, they hold lectures at their trade fairs about how you are a dangerous doctor, they contact and harass your employer, they try to dig up dirt from your personal life, or they actually threaten you with violence.”

I can attest to the fact that such methods are not limited to the United Kingdom.  Dr. Goldacre is not the only one to take on homeopathy in an elegant, rational fashion.  Drs. Edzard Ernst and Simon Singh in their epic work “Trick or Treatment” unmask the practice further (3), and in “Suckers,” Rose Shapiro nimbly shreds the usual homeopathic assertions to pieces. (4)  

Unlike Mme. Beaulieu, I will refrain from nit-picking over inconsequential historical details, such as whether my statement that “homeopathy is a specific practice conceived in the early nineteenth century by Samuel Hahnemann” is correct.  It is.  While Hahnemann did publish an article about his practice in 1796, he did not coin the term “homeopathy” until 1807 when he published his essay Indications of the Homeopathic Employment of Medicines in Ordinary Practice.  It was also Hahnemann, and not the ancient Greeks, who introduced the term “allopathy” as a pejorative term for conventional medicine.  Beaulieu’s comment that “homeopathy was never invented by Samuel Hahnemann,” as numerous history books and I maintain, “but goes back to ancient Greece,” is incorrect.  While some Greek physicians did raise the notion of “like cures like,” the idea of dilution and succession, which is the essence of homeopathy, was introduced by Hahnemann.  I won’t quibble about whether Hahnemann experimented with belladonna for sore throat or for scarlet fever.  Does it really matter how he arrived at his implausible conclusions?  In any case, Hahnemann’s Materia Medica clearly states that homeopathic belladonna is a treatment for sore throat.

Let’s get down to more important matters.  I’ve already expressed my views on the published trials of homeopathy.  The evidence, for all who care to read the scientific literature in its totality suggests that homeopathy is a placebo phenomenon.  The definitive meta-analysis published in the Lancet (5) concludes:

“Biases are present in placebo-controlled trials of both homoeopathy and conventional medicine. When account was taken for these biases in the analysis, there was weak evidence for a specific effect of homoeopathic remedies, but strong evidence for specific effects of conventional interventions. This finding is compatible with the notion that the clinical effects of homoeopathy are placebo effects.”

There have been numerous systematic reviews of homeopathy trials, and even systematic reviews of systematic reviews (6, 7).  One that is often presented by homeopaths as being favourable to their practice is the Swiss report “Homeopathy in Healthcare: Effectiveness, Appropriateness, Safety, Costs.”  Contrary to what is commonly claimed, this is not a report by the Swiss government, but rather a committee composed mostly of members who have a history of favouring alternative therapies.  Dr. Edzard Ernst, one of the world’s foremost experts on homeopathy, has dissected this review and has shown that due to omissions and misrepresentations of the conclusions of individual studies, the report is “methodologically flawed, inaccurate and biased.”(8)  Anyone interested in a thorough discussion of how the Swiss report has been twisted can check out the comments by Rudloff and Zeno (9).  The Cuban “study” that is sometimes brought up in support of homeopathy actually doesn’t provide such support, as is clearly explained by Dr. David Gorski (10).

A common argument made by homeopaths is that the placebo effect cannot work in the case of animals and infants.  This is plainly wrong as can be readily seen by carrying out a PubMed search.  It is well known that children respond to their parents’ expectations and pets to that of their owners. (11). 

The often repeated assertion that homeopathy demonstrated its efficacy in the 19th century during cholera and typhoid epidemics by virtue of having fewer fatalities in homeopathic than conventional hospitals is often trotted out.  The explanation is simple.  Back then conventional physicians engaged in bloodletting, purging and other horrific treatments that did more harm than good.  At least homeopaths subscribed to the age old dictum, “first do no harm.”  Apparently they no longer seem to abide by that rule given that homeopaths have been known to prescribe ineffective malaria prophylaxis and commonly advise against vaccination.  The claim that homeopathy can be effective against AIDS is dangerous folly and recommendations to take homeopathic products as protection against radiation are absurd.  No wonder that a parliamentary commission in the UK has advised that the National Health Service should cease the funding of homeopathy. (12)

Dr. Luc Montagnier, a Nobel Laureate, has become a shining beacon for homeopaths who claim he has validated their practice.  He has done no such thing.  Prof. P.Z. Myers gives an excellent account of Montagnier’s bizarre experiment (13) and further insightful analysis is provided by Drs. Harriet Hall and David Gorski (14, 15). Even if this experiment, which purports to detect electromagnetic signals from a homeopathically diluted DNA solution, is ever reproduced, it says nothing about curing disease.  This critical fact is never addressed by homeopaths.  Even if water had some sort of memory, so what?  How does that have anything to do with treating disease?  Montagnier’s publication is reminiscent of Professor Jacques Benveniste’s paper in Nature describing an experiment that purported to show a homeopathic effect but could not be reproduced, as well as of Professor Madeleine Ennis’ experiments that suffered the same fate in the hands of experts on British television’s Horizon series (16).

“Can so many people be wrong?” is another lame argument often advanced to buttress the crumbling edifice of homeopathy.  The simple answer is “yes.”  Popular ideas are not necessarily right.  After all, bloodletting went on for thousands of years, and at one time the notion that the earth was the center of the universe was quite popular.  But science is not a popularity contest.

While the tenets of homeopathy are marinated in pseudoscience, homeopaths can conceivably serve a useful function.  They ask a plethora of caring questions and lend a sympathetic ear, both processes that can translate to a reduction in stress and anxiety.  But problems can arise if the homeopath does not recognize a medical condition that is amenable to treatment by conventional medicine.  There are plenty of such cases, with a classic one being the case of Penelope Dingle of Australia whose tragic death has been attributed to foregoing proper care in favour of homeopathic treatment (17).

It is edifying to consider the use of a specific homeopathic remedy such as Natrum Muriaticum.  That’s common salt.  Among other medical conditions, it is used in homeopathy to treat migraines, pain, weakness and unusual weight loss.  Not necessarily benign conditions.  The best results are said to be obtained with high potency preparations such as 30C or higher.  One grain of salt dissolved in all the water on earth would not get you near a 30C dilution.  In any case, using the homeopathic concept, salt is dissolved in pure water which is then sequentially diluted and succussed.  But hasn’t that water already been in contact with salt throughout its history, as well as with millions of other substances?  Yet, it will “remember” only the salt that the homeopath added?  And what will it do with that memory?  Imprint it on a sugar pill?  And then somehow, as the water evaporates, for the final pill contains no water, that imprint is left behind, unaffected by whatever impurities the sugar may have contained, or by the sugar molecules themselves. 

A patient then swallows this pill with water that must harbour all kinds of molecular images with which it was stamped as it rampaged through rivers, flowed over waterfalls and was flushed down toilets, including that of salt.  When the pill enters the stomach, the sugar dissolves, and somehow the aura of the salt it had carried is liberated.  This aura must be different from all the other auras of salt that cruise through our body generated by the salt we eat, otherwise there would be no need for the homeopathic version.  And then what happens?  Does this aura multiply so that it can be carried around the bloodstream so that it can get to where the problem is?  And once it gets there, how does it perform a therapeutic function?  If there is to be some benefit, there must be some sort of biochemical change, since everything that happens in the body is the result of some sort of chemical activity.  So we must therefore conclude that this baffling, mysterious aura of salt, devoid of any mass, devoid of any evidence for its existence, has engaged in a chemical reaction.  Isn’t all that a little hard to swallow? 

Homeopaths retort by saying that just because science can’t explain how homeopathy works doesn’t mean it can’t work.  They routinely criticize the “mechanistic” nature of science, yet take every opportunity to cloak themselves in its garb when it suits their purpose.  Anytime there’s wind of some research that deals with the structure of water, as in the case of water molecules forming diverse clusters, homeopaths are quick to imply that this somehow supports “water memory” and its healing effects.  This is a plundering of science to support a nonsensical idea. 

Consider an analogy.  Suppose you have a theory that the crowing of a rooster brings on the light of dawn.  It flies in the face of everything known about science, but you are bent on proving you are correct.  Then you come across a phenomenon known as sonoluminescene that can be readily reproduced in the laboratory.  The sound of a high intensity ultrasonic horn immersed in a bubbly liquid causes some of the bubbles to burst and emit flashes of light.  You then rationalize that since it has been demonstrated that sound can produce light, it is possible that the crowing of a rooster brings on the light of dawn.  Obviously a preposterous conclusion.  As preposterous as suggesting that infinitely diluted solutions have some sort of healing ability because some esoteric experiments have demonstrated that water molecules can form clusters for tiny fractions of a second before they rearrange themselves to form a new pattern. 

Admittedly, one can wade through the scientific literature and find studies that support patients benefitting from homeopathic treatments, although the majority of these tend to be published in homeopathic journals.  Curiously these journals never seem to report negative studies of homeopathy.  Are we to conclude that every study undertaken by homeopaths produces a positive result?  In any case, the question isn’t whether some patients benefit from homeopathy, the question is why.  The homeopathic rationale of course is that extremely diluted and succussed solutions trigger a physiological response.  I’ve already discussed the unlikelihood of such an effect, but here’s a further question.  Have manufacturers of homeopathic remedies carried out studies on the effectiveness of diluted but not succussed solutions?  Or the effectiveness of different dilutions?  If so, why have they not published the data?

I do not feel the need to deal further with Mme Beaulieu’s dubious defense of the ability of nonexistent molecules to cure disease, or with her menacing insinuations.  But I will repeat the challenge I presented in one of my columns.  I propose that the “Syndicat des homeopathes” be given ten unlabeled vials of homeopathic remedies along with a list of what these are.  Let the members of the Syndicat use any means they desire to identify the contents of the vials.  If they can do this, we will entertain the possibility that homeopathic medications may have some efficacy other than the placebo effect.  Any suggestion that homeopathic pills contain some sort of “vital force” that is not scientifically measurable is unacceptable.  That excuse amounts to sloppy thinking sprinkled with magic dust.  Magical thinking of course is not limited to homeopathy, most of alternative medicine is permeated with it.  Richard Dawkins in an episode of the outstanding series “Enemy of Reason” brilliantly dispels the magic with science. (18)  A “must see” not only for Mme Beaulieu but for everyone!

Finally, it is incumbent on those making a claim to provide the appropriate supporting evidence, and obviously homeopaths do claim that their preparations have some sort of therapeutic activity.  Since we can assume that there is no universal homeopathic remedy, the preparations must differ from each other.  And of course, according to their labels, they do.  Therefore we can conclude that a failure to identify the contents of the unlabeled vials in the proposed experiment means that the medications are in contravention of Canadian labeling laws.  Furthermore, since the label lists ingredients that cannot be shown to be present, homeopaths must be prescribing remedies that are falsely labeled.  How does one even know whether one is getting an “active” homeopathic remedy or a fake?  Then again, does it really matter?

I would suggest that supporters of homeopathy reflect upon the words of Isaac Newton, perhaps the greatest scientist who has ever lived: "We are to admit no more causes of natural things than such as are both true and sufficient to explain their appearances.”  This can be rephrased as other things being equal, a simpler explanation is better than a more complex one.  Isn’t it more reasonable to attribute the finding of a coin under the pillow to a loving parent than to the tooth fairy?  Isn’t it more reasonable to attribute the benefits of homeopathy to the placebo effect triggered by caring practitioners than to mythical molecular auras?

Perhaps Mme Beaulieu can take some time and cogitate on these matters so that next time questions are raised about the benefits of homeopathy she is less inclined to fire off discourteous letters that do no more than serve as a testimonial to a lack of scientific acumen and critical thinking.

References:

(1)    http://www.thelancet.com/journals/lancet/article/PIIS0140673607617061/fulltext

(2)    http://www.guardian.co.uk/science/2007/nov/16/sciencenews.g2

(3)    http://www.trickortreatment.com/

(4)    http://books.google.ca/books/about/Suckers.html?id=tr4eAQAAIAAJ

(5)    http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)67177-2/abstract

(6)    http://www.ncbi.nlm.nih.gov/pubmed/12492603

(7)    http://www.smrv-journal.com/article/S1087-0792(09)00126-9/abstract

(8)    http://onlinelibrary.wiley.com/doi/10.1111/j.2042-7166.2012.01160.x/full

(9)    http://www.zenosblog.com/2012/05/that-neutral-swiss-homeopathy-report/

(10) http://scienceblogs.com/insolence/2010/11/30/homeopathy-in-cuba/

(11) http://www.sciencebasedmedicine.org/index.php/is-there-a-placebo-effect-for-animals/

(12) http://www.parliament.uk/business/committees/committees-archive/science-technology/s-t-homeopathy-inquiry

(13) http://scienceblogs.com/pharyngula/2011/01/24/it-almost-makes-me-disbelieve/

(14) http://www.sciencebasedmedicine.org/index.php/the-montagnier-homeopathy-study/

(15) http://scienceblogs.com/insolence/2010/11/23/luc-montagnier-the-nobel-disease-strikes/

(16) http://www.youtube.com/watch?v=X5wYNwstrQc

(17) http://www.danbuzzard.net/storage/Dingle_Finding.pdf

(18)http://www.youtube.com/watch?v=qONLXRNM3ss&feature=results_main&playnext=1&list=PL7CC31A5FCFE0E6D8

 

Further relevant information:

http://apgaylard.wordpress.com/2009/09/06/a-homeopathic-refutation-part-one/

http://apgaylard.wordpress.com/2009/09/13/a-homeopathic-refutation-%E2%80%93-part-two/

http://apgaylard.wordpress.com/2009/09/25/a-homeopathic-refutation-part-three/

http://sciblogs.co.nz/molecular-matters/2012/05/29/whiny-homeopaths/

http://scienceblogs.com/insolence/2012/05/14/plausibility-bias-try-reality-bias-when/

http://www.cbc.ca/news/health/story/2011/01/14/marketplace-homeopathy.html

 

Print | posted on Tuesday, June 05, 2012 8:03 PM

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# re: Answer to a Homeopath's Criticism

Left by Guy Chapman at 6/10/2012 6:17 AM
Gravatar You ask the question: "Are we to conclude that every study undertaken by homeopaths produces a positive result?". The answer, of course, is "yes". Homeopaths do not follow the scientific method, where an experiment is designed to test a hypothesis, they follow the "SCAMtific method", as used in supplemental, complementary and alternative medicine (SCAM), in which experiments are designed always to *confirm* a theory rather than test it.

But even if homeopaths ever did start conducting honest research and coming up with conflicting results, it would not matter. Homeopathy - again in common with most forms of SCAM - has no mechanism for self-correction. I am unable to find a single example where homeopathy has re-evaluated any result. No remedy that has been removed after it was found to be wrong, no proving that was rejected after it could not be replicated. For homeopaths this is considered evidence of the robustness of their field. For scientists it is a red flag indicating a complete absence of critical review. In science, even Einstein was wrong sometimes. Are we to believe that every homeopath on earth, throughout the admittedly relatively brief history of the field, has been infallible? It would seem that this is indeed what we are called to believe.

My favourite case study is oscillococcinum: a remedy based on a bacterium which does not exist and which is not in any case the causal agent for influenza, as its inventor claimed. Every single thing about oscillo is wrong (I call it the canonical quack remedy, www.chapmancentral.co.uk/.../oscillococcinum-th... since it is after all made from a duck), but it is still sold in vast quantities because homeopathy has no way of admitting it's wrong.

# re: Answer to a Homeopath's Criticism

Left by Dr. Nancy Malik at 6/10/2012 7:18 AM
Gravatar Till 2010, there have been 224 human studies published in 98 peer-reviewed international medical journals including 17 meta-analysis, 2 systematic reviews and 1 Cochrane Reviews in support of homeopathy. Out of these, 111+ are available as FULL TEXT PDF which can be downloaded at drnancymalik.wordpress.com/.../scientific-resea...
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